Arginase II inhibitory activity of flavonoid compounds from Scutellaria indica
نویسندگان
چکیده
منابع مشابه
Arginase II inhibitory activity of flavonoid compounds from Scutellaria indica
Arginase II has recently reported as a novel therapeutic target for the treatment of cardiovascular diseases such as atherosclerosis. In the course of screening plants used in natural medicines as arginase II inhibitory activity, a methanol extract of Scutellaria indica showed significant inhibitory effect. Further fractionation and repeated column chromatography led to the isolation of a new f...
متن کاملcomparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
15 صفحه اولArginase II: Atherogenesis Beyond Enzyme Activity
I t is now well established that endothelial cells (EC) and vascular smooth muscle cells (VSMC) are two specialized and interacting components of the vascular wall that orchestrate the pathogenesis of atherosclerosis through complex signaling cascades. Endothelial dysfunction is an early and critical event that initiates atherogenesis. This is mostly mediated through impaired regulation of endo...
متن کاملGlucosidase inhibitory activity and antioxidant activity of flavonoid compound and triterpenoid compound from Agrimonia Pilosa Ledeb
BACKGROUND In Chinese traditional medicine, Agrimonia pilosa Ledeb (APL) exhibits great effect on treatment of type 2 diabetes mellitus (T2DM), however its mechanism is still unknown. Considering that T2DM are correlated with postprandial hyperglycemia and oxidative stress, we investigated the α-glucosidase inhibitory activity and the antioxidant activity of flavonoid compound (FC) and triterpe...
متن کاملAldose Reductase Inhibitory Activity of Compounds from Zea mays L.
Aldose reductase (AR) inhibitors have a considerable therapeutic potential against diabetes complications and do not increase the risk of hypoglycemia. Through bioassay-guided fractionation of an EtOH extract of the kernel from purple corn (Zea mays L.), 7 nonanthocyanin phenolic compounds (compound 1-7) and 5 anthocyanins (compound 8-12) were isolated. These compounds were investigated by rat ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Pharmacal Research
سال: 2013
ISSN: 0253-6269,1976-3786
DOI: 10.1007/s12272-013-0125-3